Neonatal purpura fulminans manifestation in early-onset group B Streptococcal infection

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Neonatal purpura fulminans manifestation in early-onset group B Streptococcal infection

PATIENT Male, 0 FINAL DIAGNOSIS: Purpura fulminans Symptoms: Fever • letargy MEDICATION - Clinical Procedure: - Specialty: Pediatrics and Neonatology. OBJECTIVE Rare disease. BACKGROUND Neonatal purpura fulminans (PF) is a rare but frequently fatal disorder associated with high morbidity and mortality. It may be congenital, as a result of protein C and S deficiency, or acquired due to sev...

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Purpura Fulminans and Late Onset Group B Streptococcal Sepsis in a Premature Twin

INTRODUCTION  Purpura fulminans (PF) is a skin manifestation due to hemorrhagic infarction caused by intravascular thrombosis secondary to bacterial infections or deficiency of anticoagulants such as protein C and protein S. Neonatal PF is a rare but potentially disabling disorder associated with a high mortality and severe long term morbidity in those who survive. CASE DESCRIPTION  We report...

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Prevention of early-onset neonatal group B streptococcal disease.

Most cases of neonatal group B streptococcal disease with early onset have an intrapartum pathogenesis. Attack rates are increased substantially in infants born to mothers with prenatal group B streptococcal colonization and various perinatal risk factors (premature labor, prolonged membrane rupture, or intrapartum fever). In a randomized controlled trial, we studied the effect of selective int...

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The Prevention of Early-Onset Neonatal Group B Streptococcal Disease.

OBJECTIVE To review the evidence in the literature and to provide recommendations on the management of pregnant women in labour for the prevention of early-onset neonatal group B streptococcal disease. The key revisions in this updated guideline include changed recommendations for regimens for antibiotic prophylaxis, susceptibility testing, and management of women with pre-labour rupture of mem...

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Neonatal Purpura Fulminans

Neonatal purpura fulminans is a rare and life threatening disease that can be inherited or acquired in etiology. It manifests as DIC and extensive subcutaneous thrombosis. The condition is often fatal unless there is prompt diagnosis, and judicious therapy. The most important causes of this condition are infections and congenital deficiency of anticoagulant proteins C and S.In the case of PC (p...

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ژورنال

عنوان ژورنال: American Journal of Case Reports

سال: 2013

ISSN: 1941-5923

DOI: 10.12659/ajcr.889352